Volunteering for a Trial

Researchers are always testing new ways to treat cancer and to help improve healthcare. Choosing to participate in a clinical trial is an important personal decision. If you are considering participating in a clinical trial for a cancer therapy, please consult your physician to help you decide if a trial is right for you.

Several resources are available to help patients and their families learn more about cancer clinical trials. One helpful resource is www.CancerTrialsHelp.org*, a non-profit organization that is dedicated to providing the facts about cancer clinical trials, what they are, why they are important and how they work. Additional information may also be found on the People Living with Cancer website* (www.plwc.org).

The final choice of whether to enter a trial is up to you, but your medical team can help you weigh the options. Here are some questions you may want to ask your doctor:

• Why is this trial important to me? What is it trying to prove?
• Who is sponsoring the trial?
• What are the potential benefits and how do those potential benefits compare to other treatment options?
• Who can participate in this trial?
• What are the eligibility requirements?
• Who will monitor my care and safety?
• Who will review the information collected during the trial?
• What are the trial's tests and treatments?
• Will I be hospitalized? If so, how often and for how long?
• Will I be able to see my own doctor? Who will be in charge of my care?
• How often will I need to visit a physician's office?
• How long will the trial last?
• How will the trial and its possible side effects affect my daily life? Are there treatments to help alleviate side effects?
• What support will be available for me and my caregivers during the trial? Can I talk to other people in the trial?
• What are my out-of-pocket costs and responsibilities?
• Will my insurance company, Medicaid, or managed care plan cover these costs? Who will help me answer this question?
• What is the long-term follow-up care? Who is providing this care?

Source: www.CancerTrialsHelp.org

If, having read through the basic information on the RADIANT trial, you would like to learn more, please feel free to contact OSI directly to ask specific questions on the study.

If you are interested in seeing if any other lung cancer studies might be suitable for you, you may wish to visit www.cancer.gov* or www.lungcanceralliance.org*. The Lung Cancer Alliance website offers a Clinical Trials Matching Service which may help narrow down which studies are specifically suited to you and your medical history.

OSI Pharmaceuticals, Inc. believes clinical research should be conducted in an open environment with the objective of allowing physicians and patients to make informed decisions in the selection of available treatment options. All OSI-sponsored clinical studies with efficacy endpoints are registered on a free, publicly accessible, independent website: www.clinicaltrials.gov.

*These websites are not endorsed by OSI, and OSI is not responsible for their content.

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medical-information@osip.com

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